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Therapy for the Nevada Strain

7/30/2019

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Combination Therapy May Combat Deadly Drug-Resistant Bacteria
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Kirby Lab Outing to Tiger Mama, Boston, MA

7/21/2019

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New combinations and repurposed antibiotics active against the pandrug-resistant Nevada CRE, NDM-1 strain early release today in AAC

7/15/2019

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Our latest manuscript: "Synergistic combinations and repurposed antibiotics active against the pandrug-resistant Klebsiella pneumoniae Nevada strain."  Antimicrobial Agents and Chemotherapy early release identifies:

Highly synergistic activity of several antimicrobial combinations.
Low apramycin and spectinomycin MIC values.

CDC previously reported that none of 26 antimicrobials they tested were active against the Nevada strain.  That made the strain until now pandrug-resistant.
 
Links to several news articles about this pandrug-resistant strain::
The Atlantic. NPR, NBC, PBS. Forbes
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Candida auris antimicrobial discovery efforts highlighted in ContagionLive

7/5/2019

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"3 Drug Combinations Appear Effective Against C auris" by Jared Kaltwasser discussed work presented by Thea Brennan-Krohn at ASM Microbe 2019.
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  • Home
  • Antimicrobials
    • Legionella pneumophila
    • T4SS-dependent Gram negative pathogens
    • CRE Pathogens
    • Mechanisms of carbapenem resistance >
      • Carbapenemases | KPC | NDM-1
      • Porins
      • Efflux pumps
  • Diagnostics
  • SARS-CoV-2
  • Pathogenesis
  • About the PI
  • Personnel
  • Publications
  • Blog
  • Environment
  • Positions
  • Resources
  • Major Equipment
  • Donations
  • Comments
  • Contact Info
  • Internal Lab Resources