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Excited to be starting apramycin collaboration with Co-PI, George O'Doherty

11/18/2018

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Apramycin scaffold exploration using novel glycochemistry and SAR studies to enhance activity against Acinetobacter baumannii and other multidrug-resistant Gram-negative pathogens.

George O'Doherty
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KP Smith Speaking tomorrow at Harvard Antimicrobial Resistance Laboratory Network as well as Broad Institute collaborator, Alejandro Pironti

10/31/2018

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  • Kenneth P. Smith, PhD (Kirby Lab, BIDMC) “Bringing the reference laboratory to the bench: Use of inkjet printing technology for on-demand broth microdilution susceptibility testing”
  • Alejandro Pironti, PhD (Earl Lab, Broad Institute) “Carbapenemase-carrying plasmid found in three different bacterial genera in a single hospital over a nine-year span”
Symposium Description
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Congratulations to postdoctoral fellow KP Smith and colleagues for acceptance of SLAS Technology Manuscript

8/5/2017

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Smith KP, Richmond DL, Brennan-Krohn T, Elliott HL, Kirby JE. Development of MAST: a Microscopy-Based Antimicrobial Susceptibility Testing Platform.  SLAS Technology,  ​In press.    

Use of inkjet printing, advanced imaging, and machine learning to achieve reference standard, microdilution antimicrobial susceptibility testing readout in two hours with off-the-shelf supplies.   For any antimicrobial at will.

Update:  Now Published On-Line in SLAS Technology Website!
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Multi-Institutional CRE Genomics Study Published in PNAS 

1/20/2017

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See: www.pnas.org/content/early/2017/01/10/1616248114.abstract.  This is part of our ongoing collaboration with Ashlee Earl's group at the Broad Institute, Cambridge, MA
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Selected as a SLAS 2017 Innovation Award Finalist

1/16/2017

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I was selected as a SLAS 2017 Innovation Award Finalist and will be speaking at the SLAS Annual Meeting with a presentation titled: "Inkjet Printing Technology for Facilitated At Will Antimicrobial Susceptibility Testing (FAST) in Under 5 Hours: Addressing the Needs of a So-Called 'Post-Antibiotic Era'.
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  • Home
  • Antimicrobials
    • Legionella pneumophila
    • T4SS-dependent Gram negative pathogens
    • CRE Pathogens
    • Mechanisms of carbapenem resistance >
      • Carbapenemases | KPC | NDM-1
      • Porins
      • Efflux pumps
  • Diagnostics
  • Pathogenesis
  • About the PI
  • Personnel
  • Publications
  • Blog
  • Environment
  • Positions
  • Resources
  • Donations
  • Comments
  • Contact Info
  • Internal Lab Resources